| Autor: |
Paiva CE; Oncological and Hemato-oncological Center, Sao Paulo State University, Rua Antonio Nunes da Silva Sobrinho, 180-Jardim Paraiso II-Botucatu, Sao Paulo 18610-170, Brazil. cepaiva@fmb.unesp.br, Moraes Neto FA, Agaimy A, Custodio Domingues MA, Rogatto SR |
| Jazyk: |
angličtina |
| Zdroj: |
World journal of gastroenterology [World J Gastroenterol] 2008 Feb 07; Vol. 14 (5), pp. 800-2. |
| DOI: |
10.3748/wjg.14.800 |
| Abstrakt: |
Approximately 10% of patients with gastrointestinal stromal tumors (GIST) develop other neoplasms, either synchronously or metachronously. In this report we describe coexistence of a gastrointestinal stromal tumor and a hepatic perivascular epithelioid cell tumor (PEComa) in a 51-year-old woman with no evidence of tuberous sclerosis. A subcapsular hepatic nodule (0.8 cm in diameter) was found during surgery for symptomatic gastric neoplasm (15 cm in diameter) arising from the lesser curvature. Both tumors revealed histomorphological and immunohistochemical features confirming a diagnosis of a small incidental hepatic PEComa and a high risky extramural gastric GIST, respectively. The patient remained disease-free 25 mo after surgery with no evidence of tumor recurrence or new neoplasms. To our knowledge, this is the first report of PEComa in a patient with GIST. Hepatic lesions detected synchronously or metachronously in patients with GISTs may represent histogenetically distinct lesions and should be sampled to confirm or exclude metastatic GISTs. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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