The impact of left ventricular systolic dysfunction on survival after renal transplantation.
| Autor: | Siedlecki A; Division of Nephrology, Washington University, St. Louis, MO 63110, USA. asiedlec@im.wustl.edu, Foushee M, Curtis JJ, Gaston RS, Perry G, Iskandrian AE, de Mattos AM |
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| Jazyk: | angličtina |
| Zdroj: | Transplantation [Transplantation] 2007 Dec 27; Vol. 84 (12), pp. 1610-7. |
| DOI: | 10.1097/01.tp.0000295748.42884.97 |
| Abstrakt: | Background: Gated single photon emission computed tomography (SPECT) provides information on myocardial perfusion and left ventricular ejection fraction (LVEF), which correlates with risk of cardiac events in patients with known or suspected coronary artery disease (CAD). We hypothesize that decreased LVEF at time of renal transplant evaluation is an independent risk factor for cardiac death and nonfatal events after transplant. Methods and Results: A total of 653 recipients of renal allografts between 1998 and 2005 had stress SPECT imaging before transplantation. One hundred and nineteen (18%) patients had left ventricular (LV) systolic dysfunction (LVEF Conclusions: Systolic dysfunction is associated with increased risk for overall and cardiac-related death and nonfatal events after renal transplantation, an association independent of ischemic disease. |
| Databáze: | MEDLINE |
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