| Autor: |
O'Brien KL; Center for American Indian Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. klobrien@jhsph.edu, David AB, Chandran A, Moulton LH, Reid R, Weatherholtz R, Santosham M |
| Jazyk: |
angličtina |
| Zdroj: |
The Pediatric infectious disease journal [Pediatr Infect Dis J] 2008 Jan; Vol. 27 (1), pp. 71-3. |
| DOI: |
10.1097/INF.0b013e318159228f |
| Abstrakt: |
We report the phase III trial efficacy of 7-valent pneumococcal conjugate vaccine against clinical and culture proven otitis media (OM) among Navajo and White Mountain Apache infants. Efficacy was -0.4% (95% CI: -19.4 to 15.6) for clinically-diagnosed OM, 5.1% (95% CI: -51.5 to 40.6) for severe OM, and 64% (95% CI: -34% to 90%) for vaccine serotype pneumococcal OM suggesting that this vaccine is efficacious for pneumococcal OM in this high risk population. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
