| Autor: |
Romanova EA, Kuznetsova LG, Kubareva EA, Tsytovich AV, Merenkova IN, Oretskaia TS, Gromova ES, Shabarova ZA |
| Jazyk: |
ruština |
| Zdroj: |
Bioorganicheskaia khimiia [Bioorg Khim] 1991 Dec; Vol. 17 (12), pp. 1640-8. |
| Abstrakt: |
Phosphoramidite derivative of 9-[1'-hydroxy-2'-(hydroxymethyl)ethoxy]methylguanine (glG) is synthesized which allows one to introduce point modifications in any position of the chemically prepared oligonucleotide chain. Oligonucleotides with 5'-terminal glG can be used in chemical ligation promoted by cyanogen bromide. The modified oligonucleotide duplexes were characterized by melting curves and CD spectra. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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