Reproducibility of P3.

Autor: Zamrini EY; Department of Neurology Medical College of Georgia, Augusta 30912-3275., Meador KJ, Thompson WO, Lee GP
Jazyk: angličtina
Zdroj: The International journal of neuroscience [Int J Neurosci] 1991 Nov; Vol. 61 (1-2), pp. 113-20.
DOI: 10.3109/00207459108986279
Abstrakt: The P3 event-related potential has been widely employed in both clinical and research investigations. In the present study, P3 latency and amplitude intersession reliability were evaluated in 4 sessions over an average of 33 days in 24 healthy adults using the P3 tonal oddball paradigm. Mean group latencies ranged from 302-305 ms and mean amplitudes ranged from 7.75-8.87 microV. No significant group differences were found across sessions for latency or amplitude. Intrasubject variability was large; the 95% confidence interval for the difference between the means of two combined sessions was +/- 20 ms for latency and +/- 4.63 microV for amplitude. The results suggest that P3 latency and amplitude are reliable and reproducible over weeks for groups, but have greater variability for individuals.
Databáze: MEDLINE