| Autor: |
Tupitsyn NN; State N.N.Blokhin Russian Cancer Research Center Affiliated to the Russian Academy of Medical Sciences, Moscow, Russian Federation. cannt@aha.ru, Yaryghin VN, Bryukhovetskiy AS, Grivtsova LY, Mentkevich GL, Dolgopolov IS, Zaitsev AY, Davydov MI |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of biological regulators and homeostatic agents [J Biol Regul Homeost Agents] 2006 Jan-Jun; Vol. 20 (1-2), pp. 36-40. |
| Abstrakt: |
Immunophenotype of mobilized stem blood cells (CD34+) was studied in 29 patients with late post-traumatic spinal lesions. The CD34+ cells demonstrated different levels of expression of CD45, CD38, monomorphic determinants HLA-DR and gp130 epitopes. Most patients presented with a CD34+ cell fraction with no or low expression of common leukocytic antigen CD45. Only 2 patients had greater than 15 percent of HLA-DR-CD38- cells in the CD34+ fraction. A common transducer molecule of interleukin-6 family cytokines gp130 was expressed on stem (CD34+) cells in all the cases, 26 percent of the patients had an activated gp130 phenotype, i.e. a combination of C7+ and A1- epitopes. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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