Unexplained polyarthralgia and celiac disease.

Autor: Dawidowicz K; Rheumatology Federation, Lariboisière Teaching Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France., Ea HK, Lahalle S, Qubaja M, Lioté F
Jazyk: angličtina
Zdroj: Joint bone spine [Joint Bone Spine] 2008 May; Vol. 75 (3), pp. 325-8. Date of Electronic Publication: 2007 Oct 15.
DOI: 10.1016/j.jbspin.2007.05.016
Abstrakt: Celiac disease is an immunological disorder whose best-known manifestations are gastrointestinal symptoms. However, early joint manifestations are common and frequently overlooked features of celiac disease. We report a case in which unexplained inflammatory polyarthralgia and iron-deficiency anemia led to the diagnosis of celiac disease. Autoimmune thyroiditis was also a feature. Early diagnosis and treatment of celiac disease protect patients against complications such as digestive neoplasis. A simple and rapid tool for achieving the early diagnosis is the measurement of the serum of anti-gliadin, anti-endomysial and anti-tissue transglutaminase antibodies. However, a duodenal biopsy remains the only means of making the definitive diagnosis of celiac disease.
Databáze: MEDLINE