Reagents for the selective immobilization of oligonucleotides on solid supports.

Autor: Kvach MV; Institute of Physical Organic Chemistry NAS, Minsk, Belarus., Prokhorenko IA, Ustinov AV, Gontarev SV, Korshun VA, Shmanai VV
Jazyk: angličtina
Zdroj: Nucleosides, nucleotides & nucleic acids [Nucleosides Nucleotides Nucleic Acids] 2007; Vol. 26 (6-7), pp. 809-13.
DOI: 10.1080/15257770701503670
Abstrakt: New reagents (CPGs and phosphoramidites) for automatic solid phase synthesis of modified oligonucleotides were designed. Three oligonucleotides carrying fluorescent label at the 5'-terminus and an anchor group at the 3'-terminus were prepared and their immobilization in orthogonal conditions on solid supports was studied.
Databáze: MEDLINE
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