| Autor: |
Park S; Department of Foods and Nutrition, The University of Georgia, Athens, GA, USA., Johnson MA, Shea-Miller K, De Chicchis AR, Allen RH, Stabler SP |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of nutrition for the elderly [J Nutr Elder] 2006; Vol. 25 (3-4), pp. 105-20. |
| DOI: |
10.1300/j052v25n03_08 |
| Abstrakt: |
Hearing loss has been associated with poor vitamin B12 status in some, but not all studies. This study examined a possible relationship between age-related hearing loss and poor B12 status in 93 older adults using different indices of B12 status. Hearing loss was defined as pure-tone average threshold > 25 decibel hearing level. Participants with methylmalonic acid (MMA) > 271 nmol/L at baseline received 1,000 g/d, and those with MMA < or = 271 nmol/L were randomly assigned to receive 0, 25, or 100 microg/d of B12. In a series of logistic regression analyses, compared with participants with normal hearing, those with impaired hearing had a significantly higher serum mean MMA concentrations in the best and the worst ears and a higher prevalence of elevated MMA (> 271 nmol/L) in the worst ear only. Thus, elevated MMA concentration may be associated with hearing loss in older adults. However, short-term B12 supplementation was unrelated to improvements in hearing status in B12-deficient individuals. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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