Autor: |
Filipescu G; Victor Babeş Institute, Department of Pathology, Bucharest, Romania., Codorean E, Laky D, Tănase C, Ciotaru L |
Jazyk: |
angličtina |
Zdroj: |
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie [Rom J Morphol Embryol] 1991 Jan-Jun; Vol. 37 (1-2), pp. 49-54. |
Abstrakt: |
In acute experimental intoxication with 3 indigenous pesticides (Tripinacloraz, Lemax and Maleic Hydrazide-Na salt) the changes of some biochemical parameters, reflecting the degree of hepatic structural alterations, were studied. The pesticides were administered by gastric gavage in a single dose close to DL50 to Wistar male rats. The morphological alterations were in good correlation with a different hepatocellular levels localization. Reversible morphological lesions (granulovascuolar like dystrophy and circulatory disorders) without any pathological significance on dose-effect correlation induced a progressive response especially on serum ceruloplasmine, leucinaminopeptidase and lactatdehydrogenase. |
Databáze: |
MEDLINE |
Externí odkaz: |
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