Synthesis of benzoxazinone derivatives: a new route to 2 (N phthaloylmethyl)-4H-3,1-benzoxazin-4-one.

Autor: Shariat M; Department of Chemistry, Payamnoor University of Golpayegan, Golpayegan, Iran., Abdollahi S
Jazyk: angličtina
Zdroj: Molecules (Basel, Switzerland) [Molecules] 2004 Jul 31; Vol. 9 (8), pp. 705-12. Date of Electronic Publication: 2004 Jul 31.
DOI: 10.3390/90800705
Abstrakt: A new method has been designed to prepare the known benzoxazinone derivative 2-(N-phthaloylmethyl)-4H-3,1-benzoxazin-4-one (4). The acyl chloride derivative N-phthaloylglycine reacts with anthranilic acid in chloroform, in the presence of triethylamine, to give an intermediate that is then reacted with cyanuric chloride, used as a cyclization agent, to produce the benzoxazinone derivative.
Databáze: MEDLINE