A novel ensemble strategy for classification of prostate cancer protein mass spectra.

Autor: Assareh A; Biomedical Engineering Faculty of Amirkabir University of Technology, Tehran, Iran., Moradi MH, Esmaeili V
Jazyk: angličtina
Zdroj: Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference [Annu Int Conf IEEE Eng Med Biol Soc] 2007; Vol. 2007, pp. 5988-91.
DOI: 10.1109/IEMBS.2007.4353712
Abstrakt: Protein mass spectra pattern recognition is a new forum in which many machine learning algorithms have been conducted to enhance the chance of early cancer diagnosis. The high-dimensionality-small-sample (HDSS) problem of cancer proteomic datasets still requires more sophisticated approaches to improve the classification accuracy. In this study we present a simple ensemble strategy based on measuring the generalizing capability of different subsets of training data and apply it in making final decision. Using a limited number of biomarkers along with 5 classification algorithms, the proposed method achieved a promising performance over a well-known prostate cancer mass spectroscopy dataset.
Databáze: MEDLINE