[Phase II clinical trial of neoadjuvant hormone therapy in comparison with chemotherapy of patients with breast cancer].

Autor: Semiglazov VF, Semiglazov VV, Dashian GA, Zhil'tsova EK, Ivanov VG, Bozhok AA, Tonuzov EE, Paltuev RM, Mel'nikova OA, Klettsel' AA, Krivorot'ko PV, Donskikh RV, Kochetova IA, Damenia AO, Zernov KIu, Voskresenskiĭ DA, Bershteĭn LM
Jazyk: ruština
Zdroj: Voprosy onkologii [Vopr Onkol] 2007; Vol. 53 (4), pp. 400-8.
Abstrakt: Data are presented on a randomized study (stage II) which was undertaken to assess the efficacy of neoadjuvant chemotherapy (doxorubicin+paclitaxel) vis-a-vis endocrine therapy with aromatase inhibitors (anastrazole or exemestane) in postmenopausal women with ER-positive and/or PgR-positive tumors. Preoperative neoadjuvant chemotherapy was well tolerated and showed similar rates of overall response as compared with the latter regimen.
Databáze: MEDLINE