Prediction of atrial fibrillation following cardiac surgery using rough set derived rules.

Autor: Wiggins MC; Georgia Inst. of Technol., Atlanta, GA 30332, USA. mail@matthewcwiggins.com, Firpi HA, Blanco RR, Amer M, Dudley SC
Jazyk: angličtina
Zdroj: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference [Conf Proc IEEE Eng Med Biol Soc] 2006; Vol. 2006, pp. 4006-9.
DOI: 10.1109/IEMBS.2006.259834
Abstrakt: Atrial fibrillation (AF) and flutter are common following cardiac surgery, increasing costs and morbidity. Cardiologists need a method to discern those patients who are at high risk for this arrhythmia in order to attempt to treat them by either pharmacologic or non-pharmacologic means. We performed a retrospective analysis of 377 CABG patients, of which 94 developed AF post-operatively. Feature selection and AF occurrence prediction was performed using a multivariate regression model, and two rough set derived rule classifiers. The rough set derived feature subset performed best with an accuracy of 87%, a sensitivity of 58.5%, and a specificity of 96.5%. This shows the importance of testing feature subsets, thereby discouraging the practice of simply combining the best individual predictors. The utility of rough set theory in prediction of cardiac arrhythmia is also validated.
Databáze: MEDLINE