Sentinel lymph node biopsy in cutaneous melanoma.

Autor:	Oliveira AF; Unit of Skin Tumors, Plastic Surgery Division, Department of Surgery, Federal University of São Paulo, SP, Brazil. drandreafernandes@terra.com.br, Santos ID, Tucunduva TC, Sanches LG, Oliveira Filho RS, Simões e Silva Enokihara MM, Ferreira LM
Jazyk:	angličtina
Zdroj:	Acta cirurgica brasileira [Acta Cir Bras] 2007 Sep-Oct; Vol. 22 (5), pp. 332-6.
DOI:	10.1590/s0102-86502007000500002
Abstrakt:	Purpose: To assess the importance of sentinel lymph node biopsy in patients with cutaneous melanoma. Methods: Ninety consecutive non-randomized patients with stages I and II melanoma who underwent sentinel lymph node biopsy were followed up prospectively for six years. Results: Patients were followed up for a mean period of 30 months. Their mean age was 53.3 years, ranging from 12 to 83 years. Thirty patients were male (37.5%) and 50, female (62.5%). Sentinel lymph node was positive in 32.5% and negative in 67.5%. It was found that the thicker the tumor, the greater the incidence of positive sentinel lymph nodes. In the group of patients with positive sentinel lymph nodes, recurrence occurred in 43.5%, but in those with negative sentinel lymph nodes, in only 7%, what points out to the association of tumor recurrence and positive sentinel lymph nodes. There were no major postoperative complications. Conclusion: Sentinel lymph node biopsy was demonstrated to be a safe method for selecting patients who need therapeutic lymphadenectomy.
Databáze:	MEDLINE
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