Complex multidrug therapy in a patient with pulmonary hypertension before and after orthotopic heart transplantation. A case report.

Autor: D'Alto M; Department of Cardiology, Second University of Naples, Monaldi Hospital, Via D. Fontana 81, Naples, Italy. mic.dalto@tin.it, Alfano D, Maiello C, Sarubbi B, Santoro G, Argiento P, Galdieri N, Russo MG, Cotrufo M, Calabrò R
Jazyk: angličtina
Zdroj: Journal of cardiovascular medicine (Hagerstown, Md.) [J Cardiovasc Med (Hagerstown)] 2007 Nov; Vol. 8 (11), pp. 950-2.
DOI: 10.2459/JCM.0b013e328013fa50
Abstrakt: Pulmonary arterial hypertension represents an absolute contraindication for heart transplantation. We report the case of a 30-year-old man with end-stage heart failure due to restrictive cardiomyopathy and pulmonary arterial hypertension. A complex multidrug therapy improved pulmonary haemodynamics to the point that orthotopic heart transplantation could be carried out. At 18-month follow-up after heart transplantation, the patient's cardiac function made a full recovery. Larger prospective studies are warranted to support these results.
Databáze: MEDLINE