Autor: |
Shadyro OI; Department of Chemistry of the Belarusian State University, Nezavisimosty av. 4, Minsk, Belarus. shadyro@open.by, Sosnovskaya AA, Edimecheva IP, Ostrovskaya NI, Kazem KM, Hryntsevich IB, Alekseev AV |
Jazyk: |
angličtina |
Zdroj: |
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2007 Nov 15; Vol. 17 (22), pp. 6383-6. Date of Electronic Publication: 2007 Sep 04. |
DOI: |
10.1016/j.bmcl.2007.08.076 |
Abstrakt: |
The coenzymes Q and Vitamin K(3), as well as their synthetic analogues, have been found to inhibit free-radical processes of fragmentation of hydroxyl-containing organic compounds and oxidation of the latter by molecular oxygen. It has been established that the observed effects are due to the ability of quinones to oxidize the alpha-hydroxyl-containing carbon-centered radicals formed from the starting compounds. |
Databáze: |
MEDLINE |
Externí odkaz: |
|