Long-term outcome of first-generation metallic coronary stent implantation in patients with coronary artery disease: observational study over a decade.
| Autor: | Fujii N; Department of Cardiology, Sakakibara Heart Institute, Japan Research Promotion Society for Cardiovascular Diseases, Tokyo, Japan. norifuji2002@yahoo.co.jp, Asano R, Nagayama M, Tobaru T, Misu K, Hasumi E, Hosoya Y, Iguchi N, Aikawa M, Watanabe H, Umemura J, Sumiyoshi T |
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| Jazyk: | angličtina |
| Zdroj: | Circulation journal : official journal of the Japanese Circulation Society [Circ J] 2007 Sep; Vol. 71 (9), pp. 1360-5. |
| DOI: | 10.1253/circj.71.1360 |
| Abstrakt: | Background: In the era of drug-eluting stents, percutaneous coronary intervention (PCI) has been considered an established therapeutic modality for patients with coronary artery disease (CAD). However, little is known about the long-term prognosis. Methods and Results: Using data obtained from a single-center registry for cases of first-generation bare metallic stent (BMS) implantation, a 10-year follow-up study in patients with CAD was performed. Data for 125 serial patients (aged 62+/-9 years, 104 males) in whom a BMS was successfully implanted was analyzed. Cardiac death (n=16 [12.8%]), including sudden cardiac death (n=9 [7.2%]), non-cardiac death (n=17 [13.6%]) and non-fatal acute myocardial infarction (n=16 [12.8%]) were documented. At 10 years, cumulative probabilities of target and non-target lesion revascularization were 20.5% and 41.5%, respectively, and only 39.2% of the patients were free from cardiac events (cardiac death/myocardial infarction/unplanned revascularization). Age and left ventricular ejection fraction (LVEF) were significant predictors of total death, and LVEF and the use of diuretics were predictors of cardiac events. Conclusions: Stabilization of the initial stented site was relatively good and the majority of cardiac events might have originated in non-target lesions. Prevention of systemic arteriosclerosis progression is important for patients with CAD, even after successful PCI. |
| Databáze: | MEDLINE |
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