Risk assessment of preeclampsia in advanced maternal age by uterine arteries Doppler at 17-21 weeks of gestation.

Autor:	Sritippayawan S; Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Rama IV Rd, Pathumwan, Bangkok 10330, Thailand., Phupong V
Jazyk:	angličtina
Zdroj:	Journal of the Medical Association of Thailand = Chotmaihet thangphaet [J Med Assoc Thai] 2007 Jul; Vol. 90 (7), pp. 1281-6.
Abstrakt:	Objective: To assess the risk of preeclampsia development in elderly gravidarum by uterine arteries Doppler at 17-21 weeks' gestation. Material and Method: Pulsatility index (PI) of the uterine arteries was measured by color Doppler transabdominal sonography in 298 elderly gravida women at 17-21 weeks of gestation. The criterion for abnormal results was PI > 95th percentile of each gestational age and/or the presence of bilateral notches. The major end point was preeclampsia. Results: Ten woman (3.4%) developed preeclampsia. Two hundred and eighty-four women (95.3%) had a normal Doppler flow of uterine arteries (PI < or =95th percentile of each gestational age), and 14 woman (4.7%) had abnormal Doppler flow of uterine arteries. The sensitivity, specificity, and positive and negative predictive values for detecting preeclampsia were 20%, 95.8%, 14.3%, and 97.2%, respectively. Conclusion: Women with mean PI > 95th of each gestational age have a high risk of developing preeclampsia. With the high negative predictive value, this test may be useful to minimize unnecessary interventions.
Databáze:	MEDLINE
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