Thyrotoxic hypokalemic periodic paralysis: An overlooked pathology in western countries.

Autor: Pompeo A; Division of Internal Medicine, 'Floraspe Renzetti' Hospital, A.S.L. 103 Lanciano-Vasto, via del Mare, 1. 66034 Lanciano (Ch), Italy., Nepa A, Maddestra M, Feliziani V, Genovesi N
Jazyk: angličtina
Zdroj: European journal of internal medicine [Eur J Intern Med] 2007 Sep; Vol. 18 (5), pp. 380-90. Date of Electronic Publication: 2007 Jun 19.
DOI: 10.1016/j.ejim.2007.03.003
Abstrakt: Thyrotoxic hypokalemic periodic paralysis (THPP) is a complication of hyperthyroidism that is mostly diagnosed in Asian populations; consequently, it can be difficult to recognize in western populations. THPP represents an endocrine emergency that can result in respiratory insufficiency, cardiac arrhythmias, and death. Its differential diagnosis from the other more common forms of hypokalemic paralysis is important to avoid inappropriate therapy. Here, we discuss the main pathogenetic hypotheses, clinical features, and therapies of this disease. We also report an example of THPP management in our primary care unit.
Databáze: MEDLINE