The combined effect of age and basal follicle-stimulating hormone on the cost of a live birth at assisted reproductive technology.

Autor: Henne MB; Walter Reed ART Program, Walter Reed Army Medical Center, Washington, DC, USA., Stegmann BJ, Neithardt AB, Catherino WH, Armstrong AY, Kao TC, Segars JH
Jazyk: angličtina
Zdroj: Fertility and sterility [Fertil Steril] 2008 Jan; Vol. 89 (1), pp. 104-10. Date of Electronic Publication: 2007 Jul 31.
DOI: 10.1016/j.fertnstert.2007.02.016
Abstrakt: Objective: To predict the cost of a delivery following assisted reproductive technologies (ART).
Design: Cost analysis based on retrospective chart analysis.
Setting: University-based ART program.
Patient(s): Women aged >or=26 and Intervention(s): Logit regression using a fractional polynomial model of age and basal FSH was used to estimate the probability of a live birth. Cost analysis was applied to the resulting prediction.
Main Outcome Measure(s): The predicted probability of a live birth following ART based on a woman's age and FSH and the associated cost of a live birth.
Result(s): Analysis of 1,238 first ART cycles produced a prediction model for live birth rates following ART incorporating both age and FSH. A cost analysis based upon combination of age and FSH revealed the cost of a live birth exceeded $100,000 when the probability of a live birth fell below 15% and the cost rose exponentially at lower probabilities of live birth.
Conclusions(s): Based upon a woman's age and FSH and expected cost for a live birth using ART may be calculated. At live birth rates <5%, the cost of ART is high and greatly exceeds the cost of donor cycles. This information is vital for patient counseling.
Databáze: MEDLINE
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