Adult malignant lymphomas in University of Benin Teaching Hospital, Benin City, Nigeria--incidence and survival.
| Autor: | Omoti CE; Department ofHaematology University ofBenin Teaching Hospital P.M.B. 1111, Benin City, Nigeria. ediomoti@yahoo.com, Halim NK |
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| Jazyk: | angličtina |
| Zdroj: | Nigerian journal of clinical practice [Niger J Clin Pract] 2007 Mar; Vol. 10 (1), pp. 10-4. |
| Abstrakt: | Background: The occurrence of malignant lymphomas is worldwide and its incidence has being increasing, ranked 12th among all, cancers worldwide. We aim to determine the incidence and survival of the lymphoma patients in the Niger Delta region of Nigeria. Study Design: A study of 205 cases of lymphoma patients from 1993 to 2003. One-year survival was calculated using simple percentage of those alive and those that died before 1 year of diagnosis. Results: A total of 205 patients aged 18-72 years were studied. Non-Hodgkin's Lymphoma (NHL) was the most frequent (83%) while Hodgkin's Lymphoma (HL) had an incidence of 17%. The 1 year survival for patients with NHL and HL was 35.3% and 42.9% respectively. We found a strong association between haemoglobin (Hb) and white blood cell count (WBC) at presentation and lyear survival in NHL patients (P=0.0003; P=0.0001) and HL patients (P=0.0001; P=0.0104) respectively. Also, the mean Erythrocyte sedimentation rate (ESR) for lymphoma patients alive at lyear was significantly lower than those that died within 1 year (P=0.0001). Duration of illness before presentation was found to influence 1 year survival. Conclusion: We conclude that NHL was the most common of the lymphoma seen in young adulthood in the Niger Delta region of Nigeria. A positive correlation between survival and duration of illness at presentation and haematological counts was found. The 1 year survival is still very poor and this may not be unconnected with late presentation and other strong limiting factors. |
| Databáze: | MEDLINE |
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