Early impairment of cognitive functions in Parkinson's disease.

Autor: Stella F; Neuropsychiatry and Mental Health for Elderly, State University of Campinas, Campinas, SP, Brazil. fstella@rc.unesp.br, Gobbi LT, Gobbi S, Oliani MM, Tanaka K, Pieruccini-Faria F
Jazyk: angličtina
Zdroj: Arquivos de neuro-psiquiatria [Arq Neuropsiquiatr] 2007 Jun; Vol. 65 (2B), pp. 406-10.
DOI: 10.1590/s0004-282x2007000300008
Abstrakt: Background: Impairment in non-motor functions such as disturbances of some executive functions are also common events in Parkinson's disease patients.
Objective: To verify the performance of Parkinson's disease patients in activities requiring visuoconstructive and visuospatial skills.
Method: Thirty elderly patients with mild or moderate stages of Parkinson's disease were studied. The assessment of the clinical condition was based on the unified Parkinson's disease rating scale (56.28; SD=33.48), Hoehn and Yahr (2.2; SD=0.83), Schwab and England (78.93%), clock drawing test (7.36; SD=2.51), and mini-mental state examination (26.48; SD=10.11). Pearson's correlation and stepwise multiple regression were used for statistical analyses.
Results: The patients presented deterioration in visuospatial and visuoconstructive skills.
Conclusion: The clock drawing test proved to be a useful predictive tool for identifying early cognitive impairment in these individuals.
Databáze: MEDLINE