Gastric carcinoma: review of the results of treatment in a community teaching hospital.

Autor: Heemskerk VH; Maaslandziekenhuis, Department of Surgery, Sittard, The Netherlands. vh.heemskerk@gmail.com, Lentze F, Hulsewé KW, Hoofwijk TG
Jazyk: angličtina
Zdroj: World journal of surgical oncology [World J Surg Oncol] 2007 Jul 20; Vol. 5, pp. 81. Date of Electronic Publication: 2007 Jul 20.
DOI: 10.1186/1477-7819-5-81
Abstrakt: Background: The aim of this study is to provide data on long term results of gastric cancer surgery and in particular the D1 gastric resection.
Methods: In the period 1992-2004, 235 male and female patients with a median age of 69 and 70 years respectively, were included with a stage I through IV gastric carcinoma, of which 37% was stage IV disease. Whenever possible a gastric resection was performed. In case of obstructive tumour growth palliation was provided by means of a gastro-enterostomy.
Results: Gastrectomy with curative intent was achieved in 50%, palliative resection in 22%, palliative surgery (gastro-enterostomy) in 10% and in 18% irresectability led to surgical exploration only. Patients in the curative intent group demonstrated a 47% survival after 5 years and up to 34% after 10 years. However metastases where seen in 32% of the patients after gastrectomy with curative intent. After palliative resection one year survival was 57%, whereas 19% survived more than 3 years. Overall postoperative morbidity and mortality rates were 40% and 13% respectively.
Conclusion: Long term survival after surgery for gastric cancer is poor and is improved by early detection and radical resection. However, palliative resection showed improved survival compared to gastro-enterostomy alone or no resection at all which may be an effect of adjuvant therapy.
Databáze: MEDLINE
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