A new cytotoxic carbazole alkaloid from Clausena excavata.

Autor: Taufiq-Yap YH; Department of Chemistry, Universiti Putra Malaysia, Selangor, Malaysia. yap@fsas.upm.edu.my, Peh TH, Ee GC, Rahmani M, Sukari MA, Ali AM, Muse R
Jazyk: angličtina
Zdroj: Natural product research [Nat Prod Res] 2007 Jul 20; Vol. 21 (9), pp. 810-3.
DOI: 10.1080/14786410701258875
Abstrakt: A new carbazole alkaloid, 3-carbomethoxy-2-hydroxy-7-methoxycarbazole, Clausine-TY (1), together with two known carbazole alkaloid, Clausine-H (2) and Clausine-B (3), were isolated from the ethyl acetate extract of the stem bark of the Malaysian Clausena excavata. The structures of these compounds were elucidated by spectroscopic analyses. The new carbazole alkaloid shows significant cytotoxicity against CEM-SS cell line.
Databáze: MEDLINE