| Autor: |
Volkov EM; Kazan State Medical University, Russian Ministry of Health, Russia. emvolkov@kzn.ru, Sabirova AR, Nurullin LF, Zefirov AL |
| Jazyk: |
English; Russian |
| Zdroj: |
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2006 Dec; Vol. 142 (6), pp. 720-2. |
| DOI: |
10.1007/s10517-006-0461-0 |
| Abstrakt: |
Potential created by electrogenic ionic pumps under conditions of maximum activation in a warm standard ionic medium with K(+) after preincubation in cold potassium-free solution has two components: a higher ouabaine-insensitive "stationary" component, and a lower "regulatory" component sensitive to ouabaine, furosemide, and removal of Cl(-) or Ca(2+) from the medium. Functional heterogeneity of electrogenic ionic pumps is hypothesized implying the existence of two components: "stationary" (not regulated extracellularly) and "regulatory" (controlled and directly related to active Cl(-) transfer). |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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