| Autor: |
Gardner MB, Henderson BE, Estes JD, Rongey RW, Casagrande J, Pike M, Huebner RJ |
| Jazyk: |
angličtina |
| Zdroj: |
Cancer research [Cancer Res] 1976 Feb; Vol. 36 (2 pt 2), pp. 574-81. |
| Abstrakt: |
In several different populations of wild mice, observed over a 35-month period in laboratory geriatric colonies, a direct correlation was found between the prevalence and titer of spleen complement-fixing gs (p30) antigen and C-type particles in newly trapped healthy mice and a predilection to lymphoma and a hind leg paralytic disease upon aging. Other studies have established the indigenous C-type virus as the essential etiological determinant of both diseases in wild mice. An increased incidence of breast carcinomas, hepatomas, and pulmonary adenomas associated with C-type virus also occurred in the lymphoma-paralysis-prone colony as compared with the tumor-resistant colonies. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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