Rhabdomyolysis associated with cranial diabetes insipidus.

Autor: Kung AW; Department of Medicine, Queen Mary Hospital, University of Hong Kong., Pun KK, Lam KS, Yeung RT
Jazyk: angličtina
Zdroj: Postgraduate medical journal [Postgrad Med J] 1991 Oct; Vol. 67 (792), pp. 912-3.
DOI: 10.1136/pgmj.67.792.912
Abstrakt: Rhabdomyolysis has been reported to be associated with hyperosmolality in diabetic ketoacidosis and non-ketotic hyperosmolal state. Whether the rhabdomyolysis was due to hyperosmolality per se or whether hyperglycaemia also played a role is not clear. We hereby report a case of cranial diabetes insipidus with hypernatraemia and hyperosmolality complicated by rhabdomyolysis. None of the known risk factors, such as coma, hypokalaemia, hypophosphataemia, diabetic ketoacidosis or non-ketotic hyperosmolality, were present in this patient. We believe that severe hyperosmolality per se is an important predisposing factor for non-traumatic rhabdomyolysis, and serum muscle enzymes should be closely monitored in the management of patients with diabetes insipidus.
Databáze: MEDLINE