| Autor: |
Khalil SH; Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia., Jackson JM, Pyle RH, Robichaud M |
| Jazyk: |
angličtina |
| Zdroj: |
Annals of Saudi medicine [Ann Saudi Med] 1995 Mar; Vol. 15 (2), pp. 137-9. |
| DOI: |
10.5144/0256-4947.1995.137 |
| Abstrakt: |
During a 20 month period, 133 bone marrow samples from an equal number of patients with acute leukemia were immunophenotyped. Patients ranged in age from two to 68 years with a mean of 23 years. Eighty-four (63.2%) were classified as acute lymphocytic leukemia (ALL) with the following immunologic subclassification: common ALL 83.3%, T-cell ALL 11.9%, null-cell ALL 2.4% and 2.4% differentiated B-cell ALL. Twenty-eight cases (21%) were classified as acute myeloid leukemia (AML) and 16 cases (12%) demonstrated biphenotypic features. Concordance with morphology and cytochemistry was observed in 129 cases (97%). Four cases (3%) manifested discrepancy between immunophenotyping, morphology and cytochemistry. We conclude that immunophenotyping by flow cytometry is a useful and reliable method for classification of acute leukemia, especially when interpreted in the light of morphology and cytochemistry. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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