High prevalence of metallo-beta-lactamase and 16S rRNA methylase coproduction among imipenem-resistant Pseudomonas aeruginosa isolates in Brazil.

Autor: Doi Y; Division of Infectious Diseases, University of Pittsburgh Medical Center, Falk Medical Building Suite 3A, 3601 Fifth Avenue, Pittsburgh PA 15213, USA. doiy@dom.pitt.edu, Ghilardi AC, Adams J, de Oliveira Garcia D, Paterson DL
Jazyk: angličtina
Zdroj: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2007 Sep; Vol. 51 (9), pp. 3388-90. Date of Electronic Publication: 2007 Jun 18.
DOI: 10.1128/AAC.00443-07
Abstrakt: Rates of metallo-beta-lactamase and 16S rRNA methylase production were investigated in 51 imipenem-resistant Pseudomonas aeruginosa clinical isolates collected from hospitals in São Paulo, Brazil. Of them, 57% and 75% produced SPM-1 and RmtD, respectively. Of note, 51% produced both enzymes, suggesting that their coproduction is already common in this geographic area.
Databáze: MEDLINE