[Factors related to the presence of reflux in patients with typical symptoms of gastroesophageal reflux disease (GERD)].
| Autor: | Corsi PR; Grupo de Afecções do Esôfago, Departamento de Cirurgia, Faculdade de Ciências Médicas, Santa Casa de São Paulo, SP. r.corsi@terra.com.br, Gagliardi D, Horn M, Pochini Cde C, Oliveira Neto RM |
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| Jazyk: | portugalština |
| Zdroj: | Revista da Associacao Medica Brasileira (1992) [Rev Assoc Med Bras (1992)] 2007 Mar-Apr; Vol. 53 (2), pp. 152-7. |
| DOI: | 10.1590/s0104-42302007000200021 |
| Abstrakt: | Objective: To analyze clinical, abdominal ultrasound, upper digestive endoscopic, esophageal manometric and prolonged esophageal pH-monitoring findings in patients with typical symptoms of GERD. Methods: The study included a total of 251 patients with typical GERD symptoms. Clinical data, Body Mass Index, abdominal ultrasound aspects and upper digestive endoscopic data are reported. Manometry and esophageal pH-monitoring were performed. Results: One-hundred-and-seventy-two patients were female (68.5%). Mean age of the total was 51.8 years. Ultrasound examination revealed colelithiasis in 23 patients and PC in 21 patients. Hiatal hernia was diagnosed in 177 patients (71%), with an average size of 3.0 cm. Erosive esophagitis was found in 168 patients (66.9%) and Barrett's esophagus in 23 patients (9.2%). A combination of hiatal hernia and esophagitis was diagnosed in 131 patients (52.3%) while only 37 patients (14.7%) did not present either. The mean extension of the lower esophageal sphincter (LES) was 2.6 cm, whereas in 132 patients (52.6%) the LES was shorter. The mean pressure of the LES was 18.9 mmHg; 46 patients (18.3%) had pressures below 14 mmHg. The mean number of reflux episodes on prolonged esophageal monitoring was 42.9; the mean number of prolonged episodes of reflux was 4.6, and the mean percentage of total acid time was 8.4%. DeMeester scores were high in 175 patients (69.7%). Conclusion: In patients with typical GERD symptoms, factors influencing the presence of pathological reflux as confirmed by prolonged esophageal pH-monitoring were: age, hiatal hernia associated to erosive esophagitis, a smaller extension, low baseline pressure and smaller volume vector of the LES. |
| Databáze: | MEDLINE |
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