Turning back the clock on neurodegeneration.

Autor: Mangan KP; Department of Physiology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53719, USA., Levenson JM
Jazyk: angličtina
Zdroj: Cell [Cell] 2007 Jun 01; Vol. 129 (5), pp. 851-3.
DOI: 10.1016/j.cell.2007.05.033
Abstrakt: Does neuronal loss associated with dementia necessarily impair the ability to learn new information and recall old memories? In a recent report in Nature, Fischer et al. (2007) show that the ability to learn and remember can be reestablished in a mouse model of dementia through either environmental enrichment or chronic treatment with an inhibitor of histone deacetylase.
Databáze: MEDLINE