Are clinical symptoms more predictive than laboratory parameters for adverse maternal outcome in HELLP syndrome?
| Autor: | Cavkaytar S; Department of Obstetrics and Gynecology, Dr. Zekai Tahir Burak Woman Health Education and Research Hospital, Ankara, Turkey. sabri99@excite.com, Ugurlu EN, Karaer A, Tapisiz OL, Danisman N |
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| Jazyk: | angličtina |
| Zdroj: | Acta obstetricia et gynecologica Scandinavica [Acta Obstet Gynecol Scand] 2007; Vol. 86 (6), pp. 648-51. |
| DOI: | 10.1080/00016340601185384 |
| Abstrakt: | Background: To determine the risk factors for adverse maternal outcome among women with HELLP syndrome. Methods: Sixty-one pregnancies with hemolysis, elevated liver enzymes and low platelet count (HELLP) syndrome diagnosed antenatally were reviewed between 2003 and 2005. Maternal outcomes analyzed included eclampsia, abruptio placentae, disseminated intravascular coagulopathy (DIC), acute renal failure, need for transfusion of blood products, cesarean delivery and maternal death. Risk factors included maternal age, parity, gestational age at diagnosis, mean arterial blood pressure, headache, visual changes, nausea-vomiting, epigastric pain, blood platelet count ( Results: Eclampsia was present in 52%, abruptio placentae in 11%, and DIC in 8% of 61 women with HELLP syndrome. 23% women required transfusion of blood products, 15% had acute renal failure, and 73% had cesarean section. Women with eclampsia had significantly more headache, nausea-vomiting, visual changes and epigastric pain (p<0.05). Transfusion was significantly more frequent among women with blood platelet counts Conclusions: Clinical symptoms, such as headache, visual changes, epigastric pain and nausea-vomiting, are more predictive than laboratory parameters for adverse maternal outcomes. |
| Databáze: | MEDLINE |
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