| Autor: |
Shugaleĭ VS, Ananian AA, Miliutina NP, Chin KT, Popova LN |
| Jazyk: |
ruština |
| Zdroj: |
Nauchnye doklady vysshei shkoly. Biologicheskie nauki [Nauchnye Doki Vyss Shkoly Biol Nauki] 1991 (9), pp. 28-34. |
| Abstrakt: |
A single intraperitoneal arginine injection increases the amidopyrin demethylation on 230% and aniline hydroxylation on 74% in rat liver microsomes. For all this the rate of lipid peroxidation estimated by the number of dienic conjugates and Schiff bases does not change. At the same time the exogenous arginine decreases the lipid bilayer microviscosity on 35% and increases the degree of protein submersion into lipid matrix on 54%. The experiments in vitro confirm the fact of activation in cytochrome P-450 isoform by arginine. A possible arginine effect on microsome membrane is under discussion. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
