Autor: |
Esipova OV, Eremin SV, Zvonkova EN |
Jazyk: |
ruština |
Zdroj: |
Bioorganicheskaia khimiia [Bioorg Khim] 1991 Aug; Vol. 17 (8), pp. 1077-85. |
Abstrakt: |
Peptide Gly-L-Leu-L-Phe and its derivatives were synthesized by the C-end elongation utilizing DCC/HOBT technique and by enzymatic route with the help of papain using esters of N-benzyloxycarbonyl-glycine and -L-leucine as acyl donors have been suggested. The chemical, similarly to the enzymatic, synthesis was not accompanied by racemization. Conditions for HPLC separation and preparative isolation of the enzymatic reaction products were developed. |
Databáze: |
MEDLINE |
Externí odkaz: |
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