Autor: |
Danielson ME; 3M Pharmaceuticals, 3M Center, Building 270-4S-02, St. Paul, Minnesota 55144-1000, USA. mdanielson@biotherapharma.com, Hays DS, Kshirsagar TA, Haraldson CA, Lundquist GD, Wurst JR, Lindstrom KJ, Mackey SS, Willie DJ, Heppner PD, Leir CM, Benson KE |
Jazyk: |
angličtina |
Zdroj: |
The Journal of organic chemistry [J Org Chem] 2007 Jun 08; Vol. 72 (12), pp. 4570-3. Date of Electronic Publication: 2007 May 17. |
DOI: |
10.1021/jo070392t |
Abstrakt: |
The deprotonation and regioselective reaction of 2H-pyrazolo[3,4-c]quinolines with a variety of electrophiles is described. Electrophiles include benzaldehyde, DMF, carbon dioxide, and iodine. This method provides a direct route to a class of pharmacologically interesting compounds. |
Databáze: |
MEDLINE |
Externí odkaz: |
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