Predictors of quality-of-life improvement following pulmonary resection due to lung cancer.

Autor: Saad IA; Hospital das Clínicas, Universidade Estadual de Campinas, Rua Maria José Ferreira 116, Campinas (SP), CEP 13085-085, Brazil. iabsaad@globo.com, Botega NJ, Toro IF
Jazyk: angličtina
Zdroj: Sao Paulo medical journal = Revista paulista de medicina [Sao Paulo Med J] 2007 Jan 04; Vol. 125 (1), pp. 46-9.
DOI: 10.1590/s1516-31802007000100009
Abstrakt: Context and Objective: There is increasing involvement of health professionals in organizing protocols to determine the impact of lung surgery on functional state and activities of daily living, with the aim of improving quality of life (QoL). The objective of this study was to investigate predictors of QoL improvement among patients undergoing parenchyma resection due to lung cancer.
Design and Setting: Prospective study, at teaching hospital of Universidade Estadual de Campinas (Unicamp).
Methods: 36 patients with lung cancer diagnosis were assessed before surgery and on the 30th, 90th and 180th days after surgery. The Short-Form Health Survey (SF-36) was used as the dependent variable. The independent variables were the Hospital Anxiety and Depression (HAD) scale, a six-minute walking test (6-MWT), a visual analogue scale for pain, forced vital capacity (FVC), type of surgery and use of radiotherapy and chemotherapy. Generalized estimation equations (GEE) were utilized.
Results: The median age for these 20 men and 16 women was 55.5 +/- 13.4 years. Both FVC and 6-MWT were predictors of improvement in the physical dimensions of QoL (p = 0.011 and 0.0003, respectively), as was smaller extent of surgical resection (p = 0.04). The social component of QoL had improved by the third postoperative month (p = 0.0005).
Conclusion: The predictors that affected QoL positively were better FVC and 6-MWT results and less extensive lung resection. Three months after the surgery, an improvement in social life was already seen.
Databáze: MEDLINE
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