Firocoxib efficacy preventing urate-induced synovitis, pain, and inflammation in dogs.

Autor: Drag M; Merial Limited, 3239 Satellite Boulevard, Duluth, GA 30096, USA., Kunkle BN, Romano D, Hanson PD
Jazyk: angličtina
Zdroj: Veterinary therapeutics : research in applied veterinary medicine [Vet Ther] 2007 Spring; Vol. 8 (1), pp. 41-50.
Abstrakt: This positive-control study evaluated the efficacy of firocoxib versus carprofen, deracoxib, and meloxicam for the prevention of pain and inflammation in a urate crystal synovitis model of lameness. Lameness scoring and force plate gait analysis were used to assess efficacy. The resulting lameness scores and force plate ground reaction forces after urate crystal injection were not significantly different among the groups. Relative to each group's baseline (nonlame) score, only the firocoxib group was not significantly lame, based on lameness score, at the model's peak effect.
Databáze: MEDLINE