| Autor: |
Oluola O; Baylor College of Medicine and Perinatal Center, Texas Children's Hospital, 6621 Fannin St., FC830.17, Houston, TX 77030-2799, USA., Kong L, Fein M, Weisman LE |
| Jazyk: |
angličtina |
| Zdroj: |
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2007 Jun; Vol. 51 (6), pp. 2198-200. Date of Electronic Publication: 2007 Apr 09. |
| DOI: |
10.1128/AAC.00506-06 |
| Abstrakt: |
This study describes lysostaphin's effect against methicillin-sensitive Staphylococcus aureus in suckling rats. Standard techniques determined minimal inhibitory and bactericidal concentrations, pharmacokinetics, and efficacy. The numbers of surviving rats after vancomycin, oxacillin, and lysostaphin treatment were comparable and were different from that of controls (P < 0.00001). Lysostaphin appears effective in the treatment of neonatal S. aureus infection. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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