| Autor: |
Degelau J; Department of Internal Medicine, St Paul-Ramsey Medical Center, Minn., Somani SK, Cooper SL, Guay DR, Crossley KB |
| Jazyk: |
angličtina |
| Zdroj: |
Archives of internal medicine [Arch Intern Med] 1992 Feb; Vol. 152 (2), pp. 390-2. |
| Abstrakt: |
Rapid index case treatment and amantadine prophylaxis were implemented in two nursing homes exposed to influenza A. Facility A had no isolation of cases, and 18 of 22 cases occurred after amantadine hydrochloride therapy was initiated. Three patients exhibited amantadine-resistant virus. Facility B had day 1 isolation of the index case. A facility-wide outbreak did not occur. The experience of these facilities suggests that concurrent amantadine treatment and prophylaxis without adequate case isolation may promote further influenza A infection in a nursing facility. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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