Localized biosensing with Topas microstructured polymer optical fiber.

Autor: Emiliyanov G; COM - DTU, Department of Communications, Optics and Materials, Technical University of Denmark, Muilding 345v, 2800 Kgs. Lyngby, Denmark. gem@com.dtu.dk, Jensen JB, Bang O, Hoiby PE, Pedersen LH, Kjaer EM, Lindvold L
Jazyk: angličtina
Zdroj: Optics letters [Opt Lett] 2007 Mar 01; Vol. 32 (5), pp. 460-2.
DOI: 10.1364/ol.32.000460
Abstrakt: We present what is believed to be the first microstructured polymer optical fiber (mPOF) fabricated from Topas cyclic olefin copolymer, which has attractive material and biochemical properties. This polymer allows for a novel type of fiber-optic biosensor, where localized sensor layers may be activated on the inner side of the air holes in a predetermined section of the mPOF. The concept is demonstrated using a fluorescence-based method for selective detection of fluorophore-labeled antibodies.
Databáze: MEDLINE