Double radiofrequency ablation is more extensive with a spherical zone shape compared to single ablation in a pig liver model.
| Autor: | Oshio A; Departments of Digestive and Cardiovascular Medicine, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan., Tamaki K, Shimizu I, Fukuno H, Urata M, Ito S, Sano N |
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| Jazyk: | angličtina |
| Zdroj: | The journal of medical investigation : JMI [J Med Invest] 2007 Feb; Vol. 54 (1-2), pp. 28-34. |
| DOI: | 10.2152/jmi.54.28 |
| Abstrakt: | Objective: We compared the duration of ablation and the area of coagulation necrosis between a single ablation method (SAM) and a double ablation method (DAM) with a 'multitined expandable' electrode (LeVeen 2 cm) for radiofrequency ablation (RFA) using pig liver. Method: In the SAM group, ablation was completed after the first roll-off. In the DAM group, an additional ablation was performed to achieve a second roll-off. The comparison was made of the time required for roll-off and the extent of coagulation necrosis between the both groups. The Ellipticity index (EI) quantitatively describes the shape of the general RF ablation zone in the axial plane. Results: There was no statistically significant difference in the interval until the first roll-off between both groups (SAM group: 100.7+/-24.7 seconds vs DAM group: 103.2+/-37.7 seconds, P=0.43). In the DAM group, the interval from the start of the additional ablation until the second roll-off was 154.0+/-86.9 seconds, longer than the interval for the first roll-off (P=0.023). The extent of coagulation necrosis was significantly more extensive in the DAM group (axial diameter, mean+/-SD, 26.2+/-2.8mm) x (maximal diameter: 29.3+/-1.6mm) x (minimal diameter: 26.5+/-3.6mm) compared to the SAM group with (23.0+/-3.3mm) x (23.7+/-3.1mm) x (20.0+/-2.5mm), respectively. Although there was no statistically significant difference in the EI between both groups, macroscopically, the shape of coagulation necrosis tended to be non-spherical in the SAM group and spherical in the DAM group. Conclusions: The DAM with a 'multitined expandable' electrode was more extensive with a spherical zone shape compared to the SAM. |
| Databáze: | MEDLINE |
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