| Autor: |
Tarakin PP; Institute of Biomedical Problems, Russian Academy of Sciences, Moscow. tarakin_pavel@mail.ru, Gasnikova NM, Shenkman BS |
| Jazyk: |
English; Russian |
| Zdroj: |
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2006 Jun; Vol. 141 (6), pp. 751-4. |
| DOI: |
10.1007/s10517-006-0270-5 |
| Abstrakt: |
Effect of functional unloading on the course of degenerative process in muscles was studied in dystrophin-deficient mdx mice. Head down-hanging of animals led to a significant decrease in the cross-section area of muscle fibers, increase in the percentage of fibers with centrally located nuclei and of Evans blue-stained fibers. Gravitation unloading of 12-month-old animals with pronounced manifestations of muscular dystrophy did not inhibit this pathological process. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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