| Autor: |
Sipovskiĭ VG, Nepovorotin AI, Smirtnov AV, Dobronravov VA, Khokhlov SE, Petrishchev NN, Barabanova VV, Chefu SG, Borisova EA |
| Jazyk: |
ruština |
| Zdroj: |
Arkhiv patologii [Arkh Patol] 2006 Nov-Dec; Vol. 68 (6), pp. 29-31. |
| Abstrakt: |
One group of adult male Wistar rats received DL-homocysteine, 13.4 mg/kg body weight every day (an HC-group) while the rats underwent subtotal nephrectomy (a SN-group) and were killed 3 weeks later. Both light and electron microscopies were used to analyze obtained renal specimens. A total loss of the brush border in some proximal tubular (PT) cells and an increase of autophagosomes and emergence of the loci of disorganized cytoplasm were observed in the HC-group, while in the SN-group there was a significant increase in the number and size of secondary lysosomes and of foci of the cytoplasmic disorganization. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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