| Autor: |
Werthman P; Hahnemann University, Philadelphia, Pennsylvania., Khanna OP, Gonick P, Silverstein L, Fetzer AE, Jaffe JS, Dilcher R, Mullin E Jr, Wasko R, Nugent DM |
| Jazyk: |
angličtina |
| Zdroj: |
Urology [Urology] 1992 Jan; Vol. 39 (1), pp. 48-51. |
| DOI: |
10.1016/0090-4295(92)90040-4 |
| Abstrakt: |
We made a retrospective study of 20 men, aged fifty or under, with adenocarcinoma of the prostate to evaluate presenting symptoms, stage, grade, and therapeutic results. Sixty-five percent were found to have extracapsular spread of disease (Stage C or D). The therapy used was one or a combination of three types: radical prostatectomy, radiation therapy, and hormonal manipulation. Five of 6 patients with Stage B disease and 3 of 6 patients with Stage C disease were treated with radiation therapy. The other Stages B and C patients underwent radical prostatectomy. In all 5 of Stage B patients receiving radiation, therapy failed; the mean time to tumor recurrence was 3.2 years. Two of 3 patients with Stage C disease died of metastatic disease within three years of receiving radiation. The 4 patients (Stages B and C) who underwent radical prostatectomy are free of disease. There was a statistically higher failure rate among the radiation therapy patients with Stages B and C disease than among the surgical patients (X2 = 8.4, p less than 0.1). |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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