Antifungal drug susceptibility profile of Pichia anomala isolates from patients presenting with nosocomial fungemia.

Autor: da Matta VL; Instituto Adolfo Lutz, Av Dr. Arnaldo 351, 11 andar, São Paulo, São Paulo, Brazil 01246-901. mattav@usp.br, de Souza Carvalho Melhem M, Colombo AL, Moretti ML, Rodero L, Duboc de Almeida GM, dos Anjos Martins M, Costa SF, Souza Dias MB, Nucci M, Levin AS
Jazyk: angličtina
Zdroj: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2007 Apr; Vol. 51 (4), pp. 1573-6. Date of Electronic Publication: 2007 Jan 29.
DOI: 10.1128/AAC.01038-06
Abstrakt: In vitro susceptibility of 58 isolates of Pichia anomala to five antifungal drugs using two broth microdilution methods (CLSI and EUCAST) was analyzed. Low susceptibility to itraconazole was observed. Fluconazole, voriconazole, amphotericin B, and caspofungin showed good antifungal activity, although relatively high drug concentrations were necessary to inhibit the isolates.
Databáze: MEDLINE