Resolution of a phytobezoar with Aldoph's Meat Tenderizer.

Autor: Baker EL; Department of Pharmacy Services, Hartford Hospital, Hartford, Connecticut 06102, USA., Baker WL, Cloney DJ
Jazyk: angličtina
Zdroj: Pharmacotherapy [Pharmacotherapy] 2007 Feb; Vol. 27 (2), pp. 299-302.
DOI: 10.1592/phco.27.2.299
Abstrakt: A 58-year-old man went to his physician with complaints of midepigastric pain, flatulence, belching, and shortness of breath. During a physical examination, the patient was in no acute distress. The patient underwent an ultrasound examination, which revealed cholelithiasis, a laparoscopic cholecystectomy, which revealed chronic gallbladder disease, and esophagogastroduodenoscopy, which revealed gastritis, a hiatal hernia, and a phytobezoar. To treat the bezoar, the patient was given Adolph's Meat Tenderizer 1 teaspoonful in 8 oz of water before each meal for 7 days. This product contains papain, a proteolytic enzyme, that is thought to cleave protein linkages within bezoars. The patient's symptoms resolved with no adverse events reported, and follow-up endoscopy revealed resolution of the phytobezoar. Although a few other agents are used to treat phytobezoars, little clinical data exist on their safety and effectiveness. Adolph's Meat Tenderizer appears to be a safe and effective treatment for patients with a phytobezoar.
Databáze: MEDLINE