[Study of chemically modified hemoglobin as an artificial oxygen carrier in the model of hemorrhagic shock in dogs].

Autor: Selivanov EA, Kochetygov NI, Gerbut KA, Azhigirova MA, Viazova EP, Zeĭnalov AM, Bystrova IM, Molokovskaia EI
Jazyk: ruština
Zdroj: Biulleten' eksperimental'noi biologii i meditsiny [Biull Eksp Biol Med] 1991 Aug; Vol. 112 (8), pp. 142-4.
Abstrakt: Hemodynamic and gas-transporting properties of the chemically modified hemoglobin solution have been studied on the model of hemorrhagic shock in dog. It has been shown that the polymerized hemoglobin solution exerts the hemodynamic action just as the plasma substitute "polyglucin" does. However, in contrast to the latter, polyhemoglobin circulating in the vascular bed for a prolonged period of time increases the blood oxygen capacity and oxygen delivery to tissues with the resultant increase in body total oxygen taking-up.
Databáze: MEDLINE