| Autor: |
Trabuco EC; Division of Gynecologic Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA., Klingele CJ, Gebhart JB |
| Jazyk: |
angličtina |
| Zdroj: |
International urogynecology journal and pelvic floor dysfunction [Int Urogynecol J Pelvic Floor Dysfunct] 2007 May; Vol. 18 (5), pp. 555-63. Date of Electronic Publication: 2007 Jan 17. |
| DOI: |
10.1007/s00192-006-0288-2 |
| Abstrakt: |
Xenografts, bovine or porcine acellular collagen bioprostheses derived from dermis, pericardium, or small-intestine submucosa, were introduced to overcome synthetic mesh-related complications. Although there are eight commercially available xenografts, there is a paucity of empiric information to justify their use instead of the use of synthetic grafts. In addition, limited data are available about which graft characteristics are important and whether graft-reinforced repairs reduce recurrences and improve outcomes. To address these knowledge gaps, we conducted a Medline search of published reports on xenografts in animal and human trials. Histologic host response to implanted xenograft material depends primarily on chemical cross-linking and porosity, and it is limited to four responses: resorption, incorporation, encapsulation, and mixed. No clinical data unequivocally demonstrate an improved benefit to graft-reinforced repair. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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