[Chemoradiation therapy in conjunction with physical means of radiomodification for locally advanced laryngeal cancer].

Autor: Pankratov VA, Andreev VG, Rozhov VA, Gulibov IA, Baryshev VV, Buiakova ME, Vdovina SN, Kurpeshev OK, Podlesnykh NI, Litovkina LV
Jazyk: ruština
Zdroj: Voprosy onkologii [Vopr Onkol] 2006; Vol. 52 (2), pp. 200-2.
Abstrakt: The study deals with the results of examination and treatment of 1040 patients with cancer (T3-4N0-3M0) of larynx and laryngopharynx. Radiotherapy was given to 358 patients concurrently with systemic polychemotherapy and different means of radiomodification. The remaining patients (682) receiving the same treatment minus systemic polychemotherapy were in control. Relapse-free (72.6%) and overall survival (82.7%) in the study group was significantly higher than in controls (54.7% and 63.4%, respectively) (p < 0.001). Moreover, an organ's function was preserved in 57.1% compared with 28.5% in control (p < 0.001).
Databáze: MEDLINE